Document Detail


Adverse drug reactions in patients admitted to hospital identified by discharge ICD-10 codes and by spontaneous reports.
MedLine Citation:
PMID:  11560569     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIMS: We studied the international classification of disease (ICD) hospital discharge codes to find unreported adverse drug reactions (ADRs), and asked doctors about their attitudes to reporting some of these cases. METHODS: We examined the ICD codes assigned on discharge to identify ADRs and compared these with spontaneous reports made to the Committee on Safety of Medicines (CSM). Doctors involved were sent brief résumés of cases and asked if they would report them. RESULTS: 49 of 21 365 patient episodes were coded on discharge as ADRs, of which 33 were 'reportable'. Fourteen spontaneous reports were received by the CSM during the same period. The two groups did not overlap. 25 of 60 doctors responded to our questionnaire, and would have reported only 8 of 75 cases outlined. CONCLUSIONS: The ICD coding allowed us to identify important ADRs which most doctors would not report spontaneously.
Authors:
A R Cox; C Anton; C H Goh; M Easter; N J Langford; R E Ferner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British journal of clinical pharmacology     Volume:  52     ISSN:  0306-5251     ISO Abbreviation:  Br J Clin Pharmacol     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-09-18     Completed Date:  2001-10-11     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  7503323     Medline TA:  Br J Clin Pharmacol     Country:  England    
Other Details:
Languages:  eng     Pagination:  337-9     Citation Subset:  IM    
Affiliation:
West Midlands Centre for Adverse Drug Reaction Reporting, City Hospital NHS Trust Birmingham, B18 7QH, UK.
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MeSH Terms
Descriptor/Qualifier:
Adverse Drug Reaction Reporting Systems / standards,  statistics & numerical data*
Drug Therapy / adverse effects,  statistics & numerical data
Hospitals / statistics & numerical data*
Humans
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