Document Detail

Adverse dermatologic reaction to transdermal nitroglycerin.
MedLine Citation:
PMID:  6420136     Owner:  NLM     Status:  MEDLINE    
The incidence of adverse effects from transdermal nitroglycerin systems is reported to be very low. A cutaneous reaction from Transderm-Nitro is described. The patient in this case was a 63-year-old male with a history of chronic obstructive lung disease, adult onset diabetes mellitus, peptic ulcer disease, congestive heart failure, and angina pectoris. Seven weeks after having used a Transderm-Nitro-5 patch daily, the patient was found to have two macular erythematous areas on his chest that corresponded to the exact sites of the nitroglycerin patch. Follow-up with the same patient, using a placebo Transderm-Nitro, elicited a reaction similar in appearance. The exact causative agent is unknown, but it is believed to be from the transdermal delivery system and not the nitroglycerin.
P W Letendre; C Barr; K Wilkens
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Drug intelligence & clinical pharmacy     Volume:  18     ISSN:  0012-6578     ISO Abbreviation:  Drug Intell Clin Pharm     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-03-05     Completed Date:  1984-03-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0212457     Medline TA:  Drug Intell Clin Pharm     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  69-70     Citation Subset:  IM    
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MeSH Terms
Dermatitis, Contact / etiology*
Middle Aged
Nitroglycerin / administration & dosage,  adverse effects*
Skin Absorption
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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