| Adverse dermatologic reaction to transdermal nitroglycerin. | |
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MedLine Citation:
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PMID: 6420136 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incidence of adverse effects from transdermal nitroglycerin systems is reported to be very low. A cutaneous reaction from Transderm-Nitro is described. The patient in this case was a 63-year-old male with a history of chronic obstructive lung disease, adult onset diabetes mellitus, peptic ulcer disease, congestive heart failure, and angina pectoris. Seven weeks after having used a Transderm-Nitro-5 patch daily, the patient was found to have two macular erythematous areas on his chest that corresponded to the exact sites of the nitroglycerin patch. Follow-up with the same patient, using a placebo Transderm-Nitro, elicited a reaction similar in appearance. The exact causative agent is unknown, but it is believed to be from the transdermal delivery system and not the nitroglycerin. |
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Authors:
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P W Letendre; C Barr; K Wilkens |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Drug intelligence & clinical pharmacy Volume: 18 ISSN: 0012-6578 ISO Abbreviation: Drug Intell Clin Pharm Publication Date: 1984 Jan |
Date Detail:
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Created Date: 1984-03-05 Completed Date: 1984-03-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0212457 Medline TA: Drug Intell Clin Pharm Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 69-70 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dermatitis, Contact
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etiology* Humans Male Middle Aged Nitroglycerin / administration & dosage, adverse effects* Skin Absorption |
| Chemical | |
Reg. No./Substance:
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55-63-0/Nitroglycerin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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