Document Detail


Advantages of soft versus hard constraints in self-modeling curve resolution problems. Penalty alternating least squares (P-ALS) extension to multi-way problems.
MedLine Citation:
PMID:  18284796     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An extension to the penalty alternating least squares (P-ALS) method, called multi-way penalty alternating least squares (NWAY P-ALS), is presented. Optionally, hard constraints (no deviation from predefined constraints) or soft constraints (small deviations from predefined constraints) were applied through the application of a row-wise penalty least squares function. NWAY P-ALS was applied to the multi-batch near-infrared (NIR) data acquired from the base catalyzed esterification reaction of acetic anhydride in order to resolve the concentration and spectral profiles of l-butanol with the reaction constituents. Application of the NWAY P-ALS approach resulted in the reduction of the number of active constraints at the solution point, while the batch column-wise augmentation allowed hard constraints in the spectral profiles and resolved rank deficiency problems of the measurement matrix. The results were compared with the multi-way multivariate curve resolution (MCR)-ALS results using hard and soft constraints to determine whether any advantages had been gained through using the weighted least squares function of NWAY P-ALS over the MCR-ALS resolution.
Authors:
Selena Richards; Robert Miller; Paul Gemperline
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Applied spectroscopy     Volume:  62     ISSN:  0003-7028     ISO Abbreviation:  Appl Spectrosc     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-02-20     Completed Date:  2008-04-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372406     Medline TA:  Appl Spectrosc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  197-206     Citation Subset:  IM    
Affiliation:
Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology, and Anaesthetics, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW 7 2AZ, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
1-Butanol / chemistry
Acetic Anhydrides / chemistry
Computer Simulation
Data Interpretation, Statistical*
Models, Chemical*
Models, Statistical
Pyridines / chemistry
Spectroscopy, Near-Infrared / methods*
Chemical
Reg. No./Substance:
0/Acetic Anhydrides; 0/Pyridines; 108-24-7/acetic anhydride; 110-86-1/pyridine; 71-36-3/1-Butanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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