Document Detail


Advantages and disadvantages of trial designs: a review of analysis methods for ICD studies. AVID Investigators.
MedLine Citation:
PMID:  10879390     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
General modalities of analyses that have been used for ICD studies are reviewed. Published "typical" examples are briefly described. The historical cohort method is exemplified with previously unpublished data from the Seattle Cardiac Arrest Survivor database. The AVID Study database is used to compare the results obtained from nonrandomized methodologies with randomized methodologies. Particular issues related to the use of the ICD for example, mode of death, inability to blind, selection practice, and treatment decision times make this a natural pedagogic platform.
Authors:
A P Hallstrom; J L Anderson; L A Cobb; P L Friedman; J M Herre; R C Klein; J McAnulty; J S Steinberg
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  23     ISSN:  0147-8389     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2000-10-26     Completed Date:  2000-10-26     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1029-38     Citation Subset:  IM    
Affiliation:
Department of Biostatistics, University of Washington, Seattle 98105, USA. aph@u.washington.edu
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MeSH Terms
Descriptor/Qualifier:
Bias (Epidemiology)
Case-Control Studies
Clinical Trials as Topic / methods*
Cohort Studies
Data Interpretation, Statistical
Databases as Topic
Defibrillators, Implantable*
Humans
Randomized Controlled Trials as Topic
Research Design*
Survival Rate
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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