| Advantages of corticosteroids in managing acute bacterial postoperative endophthalmitis | |
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MedLine Citation:
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PMID: 19107051 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most studies show a trend toward a beneficial or at least neutral effect of associating corticosteroids and antibiotics. However, caution must be taken, with various factors considered: the type, virulence, and size of the inoculum, and the treatment chosen. Early intravitreal administration of 400 microg of dexamethasone seems to be beneficial in treating postoperative Staphylococcus epidermidis-related endophthalmitis. However, a large-scale prospective, randomized, controlled study is mandatory to gain evidence supporting steroid therapy in postoperative endophthalmitis. |
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Authors:
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M Saleh; F Jehl; G Prevost; C Speeg-Schatz; T Bourcier |
Publication Detail:
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Type: English Abstract; Journal Article; Review |
Journal Detail:
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Title: Journal français d'ophtalmologie Volume: 31 ISSN: 1773-0597 ISO Abbreviation: J Fr Ophtalmol Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-12-24 Completed Date: 2009-02-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7804128 Medline TA: J Fr Ophtalmol Country: France |
Other Details:
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Languages: fre Pagination: 825-33 Citation Subset: IM |
Affiliation:
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Service d'Ophtalmologie, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg. Université Louis- Pasteur, Strasbourg I. |
Vernacular Title:
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Intérêt des corticoïdes dans la prise en charge de l'endophtalmie postopératoire aiguë bactérienne. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Cortex Hormones
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administration & dosage,
therapeutic use* Animals Anti-Bacterial Agents / administration & dosage, therapeutic use Anti-Inflammatory Agents / administration & dosage, therapeutic use* Combined Modality Therapy Cytokines / physiology Drug Evaluation, Preclinical Drug Therapy, Combination Endophthalmitis / drug therapy*, etiology, surgery Humans Injections Mice Models, Biological Postoperative Complications / drug therapy*, etiology Prospective Studies Randomized Controlled Trials as Topic / statistics & numerical data Retinal Detachment / etiology, prevention & control Staphylococcal Infections / drug therapy, etiology Vitrectomy / methods Vitreous Body |
| Chemical | |
Reg. No./Substance:
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0/Adrenal Cortex Hormones; 0/Anti-Bacterial Agents; 0/Anti-Inflammatory Agents; 0/Cytokines |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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