Document Detail


Advantages of autologous blood transfusion in off-pump coronary artery bypass.
MedLine Citation:
PMID:  19833592     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: In this randomized controlled study, we investigated the effects of autologous Hemobag blood transfusion (AHBT) and allogenic blood transfusion (ABT) in off-pump coronary artery bypass (OPCAB) surgery. METHODS: Sixty patients who underwent surgery between February 2008 and August 2008 were randomized into 2 groups. The AHBT group (n = 30) consisted of patients who received autologous Hemobag blood transfusion, and the ABT group (n = 30) consisted of patients who received allogenic blood transfusion. All patients underwent OPCAB via sternotomy. The time to extubation, chest tube drainage volume, postoperative white blood cell counts, amount of blood transfusion, sedimentation rate, C-reactive protein concentration, postoperative temperature, and the presence of atelectasis were recorded in the intensive care unit. RESULTS: Intraoperative bleeding and fluid resuscitation were similar in the 2 groups (P > .05); however, there were significant decreases in postoperative blood loss, extubation period, postoperative white cell counts, sedimentation rate, incidence of atelectasis, C-reactive protein, and fever in the AHBT group compared with the ABT group (P < .05). The rate of atrial fibrillation in the AHBT group tended to be lower than in the ABT group. CONCLUSION: Autologous blood transfusion in OPCAB may be beneficial in certain cardiac surgery patients; however, these beneficial effects require further study to be proved.
Authors:
Yuksel Ela; Mustafa Emmiler; Cevdet Ugur Kocogullari; Yuksel Terzi; Remziye Gul Sivaci; Ahmet Cekirdekci
Publication Detail:
Type:  Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The heart surgery forum     Volume:  12     ISSN:  1522-6662     ISO Abbreviation:  Heart Surg Forum     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-10-16     Completed Date:  2010-01-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100891112     Medline TA:  Heart Surg Forum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E261-5     Citation Subset:  IM    
Affiliation:
Department of Anesthesiology, Kocatepe University, Afyonkarahisar, Turkey. yukselela@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Aged
Blood Loss, Surgical / physiopathology*
Blood Sedimentation
Blood Transfusion*
Blood Transfusion, Autologous*
C-Reactive Protein / metabolism
Coronary Artery Bypass, Off-Pump*
Female
Fever / blood
Humans
Inflammation Mediators / blood
Leukocyte Count
Male
Middle Aged
Postoperative Complications / blood*
Postoperative Hemorrhage / blood*
Pulmonary Atelectasis / blood
Chemical
Reg. No./Substance:
0/Inflammation Mediators; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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