Document Detail

Advancing genetic theory and application by metabolic quantitative trait loci analysis.
MedLine Citation:
PMID:  19525414     Owner:  NLM     Status:  MEDLINE    
This review describes recent advances in the analysis of metabolism using quantitative genetics. It focuses on how recent metabolic quantitative trait loci (QTL) studies enhance our understanding of the genetic architecture underlying naturally variable phenotypes and the impact of this fundamental research on agriculture, specifically crop breeding. In particular, the role of whole-genome duplications in generating quantitative genetic variation within a species is highlighted and the potential uses of this phenomenon presented. Additionally, the review describes how new observations from metabolic QTL mapping analyses are helping to shape and expand the concepts of genetic epistasis.
Danielj Kliebenstein
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review     Date:  2009-06-12
Journal Detail:
Title:  The Plant cell     Volume:  21     ISSN:  1040-4651     ISO Abbreviation:  Plant Cell     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-08-06     Completed Date:  2009-10-22     Revised Date:  2013-06-02    
Medline Journal Info:
Nlm Unique ID:  9208688     Medline TA:  Plant Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1637-46     Citation Subset:  IM    
Genetics Graduate Group and Department of Plant Sciences, University of California, Davis, California 95616, USA.
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MeSH Terms
Chromosome Mapping
Crops, Agricultural / genetics*,  metabolism
Epistasis, Genetic
Gene Duplication
Multigene Family
Plant Proteins / genetics,  metabolism
Quantitative Trait Loci*
Transcription Factors / genetics,  metabolism
Reg. No./Substance:
0/Plant Proteins; 0/Transcription Factors

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