Document Detail

Advances in volume monitoring in dialysis patients.
MedLine Citation:
PMID:  20424567     Owner:  NLM     Status:  MEDLINE    
Estimating volume status in patients on chronic dialysis is of great clinical value. Both hypervolemia and hypovolemia are associated with serious short term and long term complications, and volume status is often difficult to assess due to multiple factors affecting intravascular and extravascular volume compartments, as well as variability between patients in baseline blood pressures and physical exams. Traditional methods such as estimated dry weight (EDW) and physical exams are often not accurate because of the subjective nature of these indicators and variability between patients' baselines. This can lead to inaccurate volume status estimation and the associated complications. Furthermore, the concept of estimated dry weight is often defined based on measurements of blood pressure which may not accurately reflect volume status. In this review we describe several methods of measuring volume status in dialysis patients that may be more accurate than traditional measurements of blood pressure and dry weight estimation. These methods include dilutional techniques, imaging of vascular structures, use of biomarkers, bioimpedance analysis and online monitoring of biochemical variables during dialysis itself. We also discuss the clinical applicability and comparisons between these methods including the benefits and drawbacks of these methods and areas for future research.
P Rout; G S Sandhu; M Khattak; A Goldfarb-Rumyantzev
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Minerva urologica e nefrologica = The Italian journal of urology and nephrology     Volume:  62     ISSN:  0393-2249     ISO Abbreviation:  Minerva Urol Nefrol     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-28     Completed Date:  2010-08-13     Revised Date:  2011-04-29    
Medline Journal Info:
Nlm Unique ID:  8503649     Medline TA:  Minerva Urol Nefrol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  13-27     Citation Subset:  IM    
Division of Nephrology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
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MeSH Terms
Biological Markers
Blood Pressure Determination
Blood Volume*
Body Weight
Electric Impedance
Heart Rate
Kidney Failure, Chronic / blood,  physiopathology*,  therapy
Renal Dialysis*
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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