Document Detail

Advances in therapy for acute lung injury.
MedLine Citation:
PMID:  23089499     Owner:  NLM     Status:  In-Data-Review    
Despite advances in the therapy for acute lung injury and adult respiratory distress syndrome, mortality remains high. The iatrogenic risk of ventilator-induced lung injury might contribute to this high mortality because the lungs are hyperinflated. Low tidal volume and inspiratory pressure are surrogates for the stress and strain concept; but lung compliance, transpulmonary pressure, and chest wall elastance might differ in individual patients. In previous published studies, an increasing number of patients were treated successfully with extracorporeal support. Extracorporeal membrane oxygenation and interventional lung assist allow ultraprotective ventilation strategies. However, these assists have different technical aspects and different indications.
Vera von Dossow-Hanfstingl
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Publication Detail:
Type:  Journal Article     Date:  2012-09-01
Journal Detail:
Title:  Anesthesiology clinics     Volume:  30     ISSN:  1932-2275     ISO Abbreviation:  Anesthesiol Clin     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-10-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101273663     Medline TA:  Anesthesiol Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  629-39     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Anesthesiology, Ludwig Maximilian University, Marchioninistrasse 15, Munich 81377, Germany. Electronic address:
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