Document Detail

Advances in the role of sacral nerve neuromodulation in lower urinary tract symptoms.
MedLine Citation:
PMID:  20972546     Owner:  NLM     Status:  MEDLINE    
Sacral neuromodulation has been developed to treat chronic lower urinary tract symptoms, resistant to classical conservative therapy. The suspected mechanisms of action include afferent stimulation of the central nervous system and modulation of activity at the level of the brain. Typical neuromodulation is indicated both in overactivity and in underactivity of the lower urinary tract. In the majority of patients, a unilateral electrode in a sacral foramen and connected to a pulse generator is sufficient to achieve significant clinical results also on long term. In recent years, other urological indications have been explored.
Philip E V Van Kerrebroeck
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International urogynecology journal     Volume:  21 Suppl 2     ISSN:  1433-3023     ISO Abbreviation:  Int Urogynecol J     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-10     Completed Date:  2011-03-02     Revised Date:  2011-08-18    
Medline Journal Info:
Nlm Unique ID:  101567041     Medline TA:  Int Urogynecol J     Country:  England    
Other Details:
Languages:  eng     Pagination:  S467-74     Citation Subset:  IM    
Department of Urology, University Hospital Maastricht, Maastricht, The Netherlands.
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MeSH Terms
Cystitis, Interstitial / therapy
Electric Stimulation Therapy / methods*
Implantable Neurostimulators
Lumbosacral Plexus / physiology*
Patient Selection
Pelvic Pain / therapy
Spinal Nerve Roots / physiology*
Treatment Outcome
Urinary Bladder, Neurogenic / therapy
Urinary Tract / innervation,  physiopathology*
Urination Disorders / physiopathology,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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