Document Detail

Advances in optical imaging of the newborn infant brain.
MedLine Citation:
PMID:  14570158     Owner:  NLM     Status:  MEDLINE    
New methods of imaging the oxygenation, hemodynamics, and metabolism of the newborn infant brain are being developed, based on illumination of the head with near-infrared light. Techniques known as optical topography and optical tomography have the potential to provide valuable information about the function of the normal brain, and about a variety of cerebral pathology such as hypoxic-ischemia. Optical methods provide a unique means of monitoring brain oxygenation safely in an intensive care environment without interference with the normal handling of the infant. Studies on infants have focused on the assessment of steady-state regional cerebral perfusion and tissue oxygenation, as well as monitoring hemodynamic changes in response to sensory stimulation. Recent technological and methodological advances in this research field are reviewed, and the likely impact of optical imaging methods on the care of newborn infants is assessed.
Jeremy C Hebden
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Psychophysiology     Volume:  40     ISSN:  0048-5772     ISO Abbreviation:  Psychophysiology     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-10-22     Completed Date:  2003-11-12     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0142657     Medline TA:  Psychophysiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  501-10     Citation Subset:  IM    
Department of Medical Physics & Bioengineering, University College London, 11-20 Capper Street, London WC1E 6JA, UK.
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MeSH Terms
Brain / anatomy & histology*
Diagnostic Imaging / trends*
Infant, Newborn / physiology*
Spectroscopy, Near-Infrared

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