| Advances in nanotechnology for the management of coronary artery disease. | |
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MedLine Citation:
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PMID: 23245913 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Nanotechnology holds tremendous potential to advance the current treatment of coronary artery disease. Nanotechnology may assist medical therapies by providing a safe and efficacious delivery platform for a variety of drugs aimed at modulating lipid disorders, decreasing inflammation and angiogenesis within atherosclerotic plaques, and preventing plaque thrombosis. Nanotechnology may improve coronary stent applications by promoting endothelial recovery on a stent surface utilizing bio-mimetic nanofibrous scaffolds, and also by preventing in-stent restenosis using nanoparticle-based delivery of drugs that are decoupled from stents. Additionally, nanotechnology may enhance tissue-engineered graft materials for application in coronary artery bypass grafting by facilitating cellular infiltration and remodeling of a graft matrix. |
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Authors:
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June-Wha Rhee; Joseph C Wu |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-12-12 |
Journal Detail:
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Title: Trends in cardiovascular medicine Volume: - ISSN: 1873-2615 ISO Abbreviation: Trends Cardiovasc. Med. Publication Date: 2012 Dec |
Date Detail:
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Created Date: 2012-12-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9108337 Medline TA: Trends Cardiovasc Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Medicine, Division of Cardiology, Stanford University School of Medicine, Stanford, CA 94305, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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