Document Detail

Advances in modeling of the bovine estrous cycle: Synchronization with PGF2α.
MedLine Citation:
PMID:  22980082     Owner:  NLM     Status:  In-Data-Review    
Our model of the bovine estrous cycle is a set of ordinary differential equations which generates hormone profiles of successive estrous cycles with several follicular waves per cycle. It describes the growth and decay of the follicles and the corpus luteum, as well as the change of the key reproductive hormones, enzymes and processes over time. In this work we describe recent developments of this model towards the administration of prostaglandin F2α. We validate our model by showing that the simulations agree with observations from synchronization studies and with measured progesterone data after single dose administrations of synthetic prostaglandin F2α.
C Stötzel; J Plöntzke; W Heuwieser; S Röblitz
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Theriogenology     Volume:  78     ISSN:  1879-3231     ISO Abbreviation:  Theriogenology     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-09-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421510     Medline TA:  Theriogenology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1415-28     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Computational Systems Biology Group, Numerical Analysis and Modeling, Zuse Institute Berlin, Takustr. 7, 14195 Berlin, Germany. Electronic address:
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