Document Detail


Advances in imaging low-grade gliomas.
MedLine Citation:
PMID:  20102109     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Imaging plays a key role in the management of low-grade gliomas. The traditional view of these tumours as non-enhancing areas of increased signal on T2-weighted imaging is now accepted as being incorrect. Using new MR and PET techniques that can probe the pathological changes with in these tumours by assessing vascularity (perfusion MR), cellularity and infiltration (diffusion weighted and diffusion tensor MR), metabolism (MR spectroscopy and FDG PET) and proliferation (MR spectroscopy, methionine PET and 18F-fluorothymidine FLT PET). These tools will allow improvements in tumour grading, biopsy/therapy guidance and earlier assessment of the response to therapy.
Authors:
Stephen J Price
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Advances and technical standards in neurosurgery     Volume:  35     ISSN:  0095-4829     ISO Abbreviation:  Adv Tech Stand Neurosurg     Publication Date:  2010  
Date Detail:
Created Date:  2010-01-27     Completed Date:  2010-02-25     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7501064     Medline TA:  Adv Tech Stand Neurosurg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-34     Citation Subset:  IM    
Affiliation:
Academic Neurosurgery Division, Department of Clinical Neurosciences, Addenbrooke's Hospital, Cambridge, UK.
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MeSH Terms
Descriptor/Qualifier:
Brain Neoplasms / diagnosis*,  metabolism,  pathology
Glioma / diagnosis*,  metabolism,  pathology
Humans
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Positron-Emission Tomography
Tomography, X-Ray Computed

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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