| Advances in identifying beryllium sensitization and disease. | |
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MedLine Citation:
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PMID: 20195436 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Beryllium is a lightweight metal with unique qualities related to stiffness, corrosion resistance, and conductivity. While there are many useful applications, researchers in the 1930s and 1940s linked beryllium exposure to a progressive occupational lung disease. Acute beryllium disease is a pulmonary irritant response to high exposure levels, whereas chronic beryllium disease (CBD) typically results from a hypersensitivity response to lower exposure levels. A blood test, the beryllium lymphocyte proliferation test (BeLPT), was an important advance in identifying individuals who are sensitized to beryllium (BeS) and thus at risk for developing CBD. While there is no true "gold standard" for BeS, basic epidemiologic concepts have been used to advance our understanding of the different screening algorithms. |
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Authors:
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Dan Middleton; Peter Kowalski |
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Publication Detail:
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Type: Journal Article; Review; Validation Studies Date: 2010-01-13 |
Journal Detail:
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Title: International journal of environmental research and public health Volume: 7 ISSN: 1660-4601 ISO Abbreviation: Int J Environ Res Public Health Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-03-02 Completed Date: 2010-05-25 Revised Date: 2010-09-30 |
Medline Journal Info:
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Nlm Unique ID: 101238455 Medline TA: Int J Environ Res Public Health Country: Switzerland |
Other Details:
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Languages: eng Pagination: 115-24 Citation Subset: IM |
Affiliation:
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Division of Health Studies, Agency for Toxic Substances and Disease Registry, Atlanta, GA 30341, USA. dcm2@cdc.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Berylliosis
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diagnosis* Beryllium / immunology, toxicity* Humans Models, Theoretical Probability Theory |
| Chemical | |
Reg. No./Substance:
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7440-41-7/Beryllium |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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