| Advances in cardiovascular genetics and embryology: role of transcription factors in congenital heart disease. | |
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MedLine Citation:
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PMID: 11021417 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In spite of tremendous advances in diagnosis and treatment of cardiovascular disease in the young, our understanding of its cause is still incomplete. Recent studies have reported pleiotropic cardiac malformations resulting from mutations in transcription factors, a family of proteins known to play important roles in many aspects of development. Further evaluation of these important causes of cardiovascular disease in the young promises new insight into embryology of cardiac development and improved understanding of the pathophysiologic basis of cardiovascular disease in the young. |
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Authors:
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D W Benson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current opinion in pediatrics Volume: 12 ISSN: 1040-8703 ISO Abbreviation: Curr. Opin. Pediatr. Publication Date: 2000 Oct |
Date Detail:
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Created Date: 2001-01-10 Completed Date: 2001-03-22 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9000850 Medline TA: Curr Opin Pediatr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 497-500 Citation Subset: IM |
Affiliation:
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Pediatric Cardiology, Medical University of South Carolina, Charleston, USA. bensondw@musc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cardiovascular Diseases
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genetics Heart / embryology Heart Defects, Congenital / diagnosis, genetics*, physiopathology Humans Molecular Biology Pedigree Risk Factors Transcription Factors / genetics* |
| Chemical | |
Reg. No./Substance:
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0/Transcription Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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