Document Detail


Advances in Resuscitation in the Setting of Vascular Injury.
MedLine Citation:
PMID:  21502108     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Damage control surgery with the principles of expeditious control of hemorrhage and contamination, followed by predominant crystalloid resuscitation in the intensive care unit has saved the lives of many severely injured trauma patients. Unfortunately, crystalloid resuscitation has too often led to worsening of coagulopathy in the setting of vascular injury. The recent conflicts in Iraq and Afghanistan have created injured patients with severe vascular injury and massive soft tissue destruction creating early and profound coagulopathy associated with high rates of mortality. An alternative strategy, known as damage control resuscitation, with the principal resuscitation of a 1:1 ratio of packed red blood cells and fresh frozen plasma has been developed during these conflicts. This method is associated with decreased mortality and improved limb salvage in military and civilian trauma patients.
Authors:
Charles J Fox; Jonathan N Bowman
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-17
Journal Detail:
Title:  Perspectives in vascular surgery and endovascular therapy     Volume:  -     ISSN:  1521-5768     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100970607     Medline TA:  Perspect Vasc Surg Endovasc Ther     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Walter Reed Army Medical Center, USA, 31st Combat Support Hospital, Afghanistan and Uniformed Services University of the Health Sciences Bethesda, MD, USA.
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