| Advances in Non-invasive Prenatal Diagnosis. | |
| | |
MedLine Citation:
|
PMID: 23422474 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
The invasive procedures amniocentesis and chorionic villus sampling are routinely applied in pregnancies at risk for fetal genetic disorders and the results obtained are the gold standard for prenatal diagnosis. These procedures have an approximately 0.5-1% risk for fetal loss and are mainly used in cases at risk for fetal chromosomal abnormalities and single-gene disorders. Identification of cell-free fetal nucleic acids (DNA and RNA) in maternal plasma and the recognition that they represent a useful source of fetal genetic material for prenatal diagnosis has led to intensive efforts to develop non-invasive prenatal testing. This review summarizes recent developments in the field of non-invasive prenatal diagnosis through the use of cell-free fetal nucleic acids in maternal circulation during pregnancy and provides an overview of the possibilities for future clinical applications. |
| | |
Authors:
|
Aristeidis G Vaiopoulos; Kalliopi C Athanasoula; Nikolas Papantoniou; Aggeliki Kolialexi |
Related Documents
:
|
21914414 - Morbidly adherent placenta: can we limit the aftermath? 7941994 - Non-traumatic rupture of kidney in pregnancy--case report and review. 15163324 - Acute promyelocytic leukaemia presenting as postpartum haemorrhage. 22197274 - International consensus and practical guidelines on the gynecologic and obstetric manag... 10401964 - Preventing the high-risk sexual behavior of adolescents: focus on hiv/aids transmission... 7576174 - How to deal with a rare entity: the coexistence of a complete mole and a healthy egg in... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: In vivo (Athens, Greece) Volume: 27 ISSN: 1791-7549 ISO Abbreviation: In Vivo Publication Date: 2013 Mar |
Date Detail:
|
Created Date: 2013-02-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8806809 Medline TA: In Vivo Country: Greece |
Other Details:
|
Languages: eng Pagination: 165-70 Citation Subset: IM |
Affiliation:
|
M.Sc., Department of Medical Genetics, Athens University School of Medicine, Aghia Sofia Children's Hospital, Thivon & Levadias, 115 27, Athens, Greece. avaiopoulos@gmail.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Description of the developmental patterns of epithelial cells and cancers originating from them will...
Next Document: Smoking cessation strategies in patients with lung disease.