| Advances in Magnetic Resonance Imaging: How They Are Changing the Management of Prostate Cancer. | |
| | |
MedLine Citation:
|
PMID: 21367519 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
CONTEXT: Although magnetic resonance imaging (MRI) is emerging as the most commonly used imaging modality for prostate cancer (PCa) detection, treatment planning, and follow-up, its acceptance has not been uniform. Recently, great interest has been shown in multiparametric MRI, which combines anatomic T2-weighted (T2W) imaging with MR spectroscopic imaging (MRSI), dynamic contrast-enhanced MRI (DCE-MRI), and diffusion-weighted imaging (DWI). OBJECTIVE: The aim of this article is to review the current roles of these MR techniques in different aspects of PCa management: initial diagnosis, biopsy strategies, planning of radical prostatectomy (RP) and external radiation therapy (RT), and implementation of alternative focal therapies. EVIDENCE ACQUISITION: The authors searched the Medline and Cochrane Library databases (primary fields: prostatic neoplasm, magnetic resonance). The search was performed without language restriction from January 2008 to November 2010. EVIDENCE SYNTHESIS: Initial diagnosis: The data suggest that the combination of T2W MRI and DWI or MRSI with DCE-MRI has the potential to guide biopsy to the most aggressive cancer foci in patients with previously negative biopsies, increasing the accuracy of the procedure. Transrectal MR-guided prostate biopsy can improve PCa detection, but its availability is still limited and the examination time is rather long. Planning of RP: It appears that adding MRSI, DWI, and/or DCE-MRI to T2W MRI can facilitate better preoperative characterization of cancer with regard to location, size, and relationship to prostatic and extraprostatic structures, and it may also facilitate early detection of local recurrence. Thus, use of these MR techniques may improve surgical, oncologic, and functional management. Planning of external RT and focal therapies: MR techniques have similar potential in these areas, but the published data remain very limited. CONCLUSIONS: MRI technology is continuously evolving, and more extensive use of MRI technology in clinical trials and practice will help to improve PCa diagnosis and treatment planning. |
| | |
Authors:
|
Alessandro Sciarra; Jelle Barentsz; Anders Bjartell; James Eastham; Hedvig Hricak; Valeria Panebianco; J Alfred Witjes |
Related Documents
:
|
12583859 - Ultrasound and angiography in the selection of patients for carotid endarterectomy. 20418649 - Soft tissue sarcoma of the thigh: need for angiography in the developing countries. 9973909 - Correlation of angiography and mr imaging in cerebral vasculitis. 16174929 - Basilar artery occlusion. 9119519 - Conventional and ct angiographic diagnosis of takayasu arteritis. 9124109 - Mr angiography of patients with peripheral arterial disease before and after translumin... 3614619 - Stir sequences in nmr imaging of the optic nerve. 21075559 - Effect of immobilization and performance status on intrafraction motion for stereotacti... 20417459 - Brain imaging findings in dyslexia. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-2-23 |
Journal Detail:
|
Title: European urology Volume: - ISSN: 1873-7560 ISO Abbreviation: - Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-3-3 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7512719 Medline TA: Eur Urol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 European Association of Urology. Published by Elsevier B.V. All rights reserved. |
Affiliation:
|
Department of Urology, Sapienza University of Rome, Rome, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The impact of targeted molecular therapies on the level of renal cell carcinoma vena caval tumor thr...
Next Document: Polynuclear aromatic hydrocarbons (PAHs) mediate cadmium toxicity to an emergent wetland species.