Document Detail

Advanced heart block aggravated by carbamazepine.
MedLine Citation:
PMID:  1148068     Owner:  NLM     Status:  MEDLINE    
This report presents a serious adverse reaction to the anticonvulsant compound carbamazepine. A woman was admitted to hospital for recurrent attacks of syncope. She suffered from atrioventricular block of the Mobitz type II. Carbamazepine suppressed the conduction in her already defective Purkinje fibres and induced ventricular stand-still with subsequent Adams-Stokes attacks.
B Beermann; O Edhag; H Vallin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British heart journal     Volume:  37     ISSN:  0007-0769     ISO Abbreviation:  Br Heart J     Publication Date:  1975 Jun 
Date Detail:
Created Date:  1975-11-01     Completed Date:  1975-11-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0370634     Medline TA:  Br Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  668-71     Citation Subset:  AIM; IM    
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MeSH Terms
Adams-Stokes Syndrome / chemically induced
Carbamazepine / adverse effects*,  pharmacology,  therapeutic use
Heart Block / chemically induced*,  drug therapy
Heart Conduction System / drug effects
Syncope / drug therapy
Reg. No./Substance:

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