Document Detail

Adulticidal activity of essential oil of Lantana camara leaves against mosquitoes.
MedLine Citation:
PMID:  20418559     Owner:  NLM     Status:  MEDLINE    
BACKGROUND & OBJECTIVES: Development of insect resistance to synthetic pesticides, high operational cost and environmental pollution have created the need for developing alternative approaches to control vector-borne diseases. In the present study we have investigated the insecticidal activity of essential oil isolated from the leaves of Lantana camara against mosquito vectors.
METHODS: Essential oil was isolated from the leaves of L. camara using hydro-distillation method. Bioassay test was carried out by WHO method for determination of adulticidal activity against mosquitoes. Different compounds were identified by gas chromatography-mass spectrometry analysis.
RESULTS: LD(50) values of the oil were 0.06, 0.05, 0.05, 0.05 and 0.06 mg/cm(2) while LD(90) values were 0.10, 0.10, 0.09, 0.09 and 0.10 mg/cm(2) against Ae. aegypti, Cx. quinquefasciatus, An. culicifacies, An. fluvialitis and An. stephensi respectively. KDT(50) of the oil were 20, 18, 15, 12, and 14 min and KDT(90) values were 35, 28 25, 18, 23 min against Ae. aegypti, Cx. quinquefasciatus, An. culicifacies, An. fluviatilis and An. stephensi, respectively on 0.208 mg/cm(2) impregnated paper. Studies on persistence of essential oil of L. camara on impregnated paper revealed that it has more adulticidal activity for longer period at low storage temperature. Gas chromatographic-mass spectrometric analysis of essential oil showed 45 peaks. Caryophyllene (16.37%), eucalyptol (10.75%), alpha-humelene (8.22%) and germacrene (7.41%) were present in major amounts and contributed 42.75 per cent of the total constituents.
INTERPRETATION & CONCLUSIONS: Essential oil from the leaves of L. camara possesses adulticidal activity against different mosquito species that could be utilized for development of oil-based insecticide as supplementary to synthetic insecticides.
V K Dua; A C Pandey; A P Dash
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Indian journal of medical research     Volume:  131     ISSN:  0971-5916     ISO Abbreviation:  Indian J. Med. Res.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-04-26     Completed Date:  2010-07-29     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  0374701     Medline TA:  Indian J Med Res     Country:  India    
Other Details:
Languages:  eng     Pagination:  434-9     Citation Subset:  IM    
National Institute of Malaria Research (ICMR), Field Unit, Haridwar , India.
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MeSH Terms
Biological Assay
Culicidae / drug effects*
Drug Evaluation, Preclinical / methods
Gas Chromatography-Mass Spectrometry / methods
Insect Repellents / pharmacology
Lantana / metabolism*
Mosquito Control / methods*
Oils, Volatile / metabolism
Pesticides / pharmacology
Plant Extracts / pharmacology
Plant Leaves / metabolism*
Reg. No./Substance:
0/Insect Repellents; 0/Oils, Volatile; 0/Pesticides; 0/Plant Extracts

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