| Adulteration of mustard cooking oil with argemone oil: do Indian food regulatory policies and antioxidant therapy both need revisitation? | |
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MedLine Citation:
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PMID: 17280492 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Consumption of adulterated mustard oil (Brassica nigra) with argemone oil (Argemone mexicana) even for a short duration leads to a clinical condition referred as epidemic dropsy. In humans, argemone oil contained in adulterated mustard oil causes oxidative stress and death of red blood cells via met-hemoglobin formation by altering pyridine nucleotide(s) and glutathione redox potential. Argemone oil contamination poses a serious threat to human health and should be checked by appropriate regulatory measures. Antioxidant therapy provides symptomatic relief and should be seriously considered for therapeutic interventions against argemone oil toxicity. |
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Authors:
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Challagundla Kishore Babu; Subhash Kumar Khanna; Mukul Das |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Antioxidants & redox signaling Volume: 9 ISSN: 1523-0864 ISO Abbreviation: Antioxid. Redox Signal. Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-02-06 Completed Date: 2007-04-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888899 Medline TA: Antioxid Redox Signal Country: United States |
Other Details:
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Languages: eng Pagination: 515-25 Citation Subset: IM |
Affiliation:
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Food Toxicology Laboratory, Industrial Toxicology Research Centre, Lucknow, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antioxidants
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therapeutic use* Edema / chemically induced, drug therapy* Erythrocytes / drug effects, metabolism Glutathione / metabolism Glutathione Disulfide / metabolism Humans India Lipid Peroxidation / drug effects Models, Biological Mustard Plant NAD / metabolism Nutrition Policy Oxidation-Reduction / drug effects Plant Oils / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Plant Oils; 0/argemone oil; 27025-41-8/Glutathione Disulfide; 53-84-9/NAD; 70-18-8/Glutathione; 8007-40-7/mustard oil |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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