Document Detail


Adult neuroblastoma complicated by increased intracranial pressure: a case report and review of the literature.
MedLine Citation:
PMID:  25328733     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Neuroblastoma is the third most commonly occurring malignancy of the pediatric population, although it is extremely rare in the adult population. In adults, neuroblastoma is often metastatic and portends an extremely poor overall survival. Our case report documents metastatic neuroblastoma occurring in a healthy 29-year-old woman whose course was complicated by an unusual presentation of elevated intracranial pressures. The patient was treated with systemic chemotherapy, I(131) metaiodobenzylguanidine (MIBG) radiotherapy, and autologous stem cell transplant (SCT). Unfortunately the patient's response to therapy was limited and she subsequently died. We aim to review neuroblastoma in the context of increased intracranial pressure and the limited data of neuroblastoma occurring in the adult population, along with proposed treatment options.
Authors:
Patrick L Stevens; Douglas B Johnson; Mary Ann Thompson; Vicki L Keedy; Haydar A Frangoul; Kristen M Snyder
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Publication Detail:
Type:  Journal Article     Date:  2014-09-25
Journal Detail:
Title:  Case reports in oncological medicine     Volume:  2014     ISSN:  2090-6706     ISO Abbreviation:  Case Rep Oncol Med     Publication Date:  2014  
Date Detail:
Created Date:  2014-10-20     Completed Date:  2014-10-20     Revised Date:  2014-10-22    
Medline Journal Info:
Nlm Unique ID:  101581035     Medline TA:  Case Rep Oncol Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  341980     Citation Subset:  -    
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