Document Detail

Adult metachromatic leukodystrophy: neurophysiologic findings.
MedLine Citation:
PMID:  4069371     Owner:  NLM     Status:  MEDLINE    
The visual and somatosensory evoked potentials were delayed in two cases of the adult form of metachromatic leukodystrophy. Brainstem auditory evoked potentials were normal. The conduction velocity along peripheral nerves was 50% slowed in one case and near normal in the other. The findings are compatible with demyelination in the central and peripheral nervous systems. The diagnosis of metachromatic leukodystrophy should be considered in cases of early dementia, with or without psychosis or other neurologic deficits, in which evoked potentials are delayed and peripheral nerve conduction is slowed.
C H Wulff; W Trojaborg
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Neurology     Volume:  35     ISSN:  0028-3878     ISO Abbreviation:  Neurology     Publication Date:  1985 Dec 
Date Detail:
Created Date:  1986-01-03     Completed Date:  1986-01-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401060     Medline TA:  Neurology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1776-8     Citation Subset:  AIM; IM    
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MeSH Terms
Brain / physiopathology
Evoked Potentials
Leukodystrophy, Metachromatic / physiopathology*
Neural Conduction
Peripheral Nerves / physiopathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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