| Adult living donor liver transplantation: body mass index and MELD score of recipients are independent risk factors for hospital mortality. | |
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MedLine Citation:
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PMID: 18512070 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND AND AIMS: Adult living donor liver transplantation (LDLT) has been established as elective procedure or urgent procedure to save the life of patients with terminal liver diseases. The outcome of LDLT varies between transplant centers. Here, we aim to evaluate the outcome of LDLT in our center and to identify the risk factors that are associated with hospital mortality of recipients. PATIENTS AND METHODS: A cohort study with 32 consecutive cases of adult living donor liver transplantation was conducted in two cooperated medical centers. Perioperative data, incidence of postoperative complications, and hospital mortality were analyzed. RESULTS: No major surgical complications and no hospital mortality were observed in all 32 donors. All donors were discharged with normal liver function with median intensive care unit (ICU) stay of 1 day and median hospital stay of 10 days. All recipients had normal liver function in early posttransplant period. Eighty-one percent of the recipient survived with normal liver function for more than 1 year. The pretransplant ICU stay, renal failure, international normalized ratio (>1.8), and Model for End-stage Liver Disease (MELD) score (>20) were independent risk factors for hospital mortality of recipients. CONCLUSIONS: Adult living donor liver transplantation should be reserved to less "sick" patients in the era of organ allocation based on MELD score. |
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Authors:
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Tung-Yu Tsui; Marcus N Scherer; Andreas A Schnitzbauer; Hans J Schlitt; Aiman Obed |
Publication Detail:
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Type: Journal Article; Multicenter Study Date: 2008-05-30 |
Journal Detail:
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Title: Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie Volume: 394 ISSN: 1435-2451 ISO Abbreviation: Langenbecks Arch Surg Publication Date: 2009 Mar |
Date Detail:
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Created Date: 2009-02-03 Completed Date: 2009-07-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9808285 Medline TA: Langenbecks Arch Surg Country: Germany |
Other Details:
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Languages: eng Pagination: 235-41 Citation Subset: IM |
Affiliation:
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Department of Surgery, University of Regensburg Medical Center, Regensburg, Germany. tung-yu.tsui@klinik.uni-regensburg.de |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Body Mass Index* Cause of Death Cohort Studies Female Follow-Up Studies Germany Hepatectomy / methods Hospital Mortality Humans Jordan Kidney Failure / complications, mortality Length of Stay / statistics & numerical data Liver Failure / classification, surgery* Liver Function Tests* Liver Transplantation / mortality* Living Donors / statistics & numerical data* Male Middle Aged Postoperative Complications / mortality* Prognosis Risk Factors Tissue and Organ Harvesting / methods Young Adult |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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