Document Detail

Adult ischemic necrotizing enterocolitis.
MedLine Citation:
PMID:  20642975     Owner:  NLM     Status:  MEDLINE    
A 66-year-old male presented with posterior myocardial infarction and painless rectal bleeding. He was treated for acute coronary event but despite extensive investigations the cause of his lower gastrointestinal bleeding remained elusive. Patient died 5 days after admission. Postmortem examination showed evidence of severe atherosclerosis and thrombosis in branches of abdominal aorta leading to bowel ischemia with multiple perforations and necrosis. The findings are consistent with the diagnosis of necrotizing enterocolitis (NEC). Main factors responsible for pathogenesis of NEC are bowel ischemia and bacterial infection. It can be classified into 3 stages according to the level of severity. Treatment ranges from mainly supportive in the initial phase to surgery in severe cases.
T Mitchell; E Christie; Habib Syed; A Koulaouzidis; W C Tan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  20     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-20     Completed Date:  2010-09-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  412-3     Citation Subset:  IM    
Gastroenterology Unit, Warrington General Hospital, Cheshire, UK.
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MeSH Terms
Atherosclerosis / complications
Enterocolitis, Necrotizing / complications*,  diagnosis*
Fatal Outcome
Gastrointestinal Hemorrhage / etiology*
Intestine, Small / blood supply*
Ischemia / etiology*
Myocardial Infarction / complications
Regional Blood Flow

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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