Document Detail

Adult human valve dimensions and their surgical significance.
MedLine Citation:
PMID:  6229998     Owner:  NLM     Status:  MEDLINE    
After cardiac valve replacement, some patients may show little improvement in functional status, in part because their prosthesis is restrictive. Guidelines were sought for valve replacement from measurements of valve circumference and calculated circularized orifice area in 160 postmortem hearts from adults with and without congestive cardiac failure. Multivariate analysis was used to relate valve area to age, sex, height, body surface area and cardiac failure. Only sex and cardiac failure were significantly related to valve area. Body surface area and other variables were poorly related to valve area. The mean (+/- standard deviation) circularized orifice area for adult male (M) and female (F) heart valves in the absence of cardiac failure were: Aortic, M 4.81 +/- 1.30, F 3.73 +/- 0.98; pulmonary, M 4.88 +/- 1.25, F 4.32 +/- 1.03; mitral, M 8.70 +/- 2.08, F 6.94 +/- 1.41; and tricuspid, M 11.9 +/- 2.72, F 9.33 +/- 2.02. In cardiac failure, atrioventricular valves enlarge (p less than 0.004). Guided by these dimensions, the surgeon can aim to insert a prosthesis of appropriate size. Comparison of these sizes with the manufacturer's calculated area for current prostheses shows that most mechanical valves and bioprostheses are potentially restrictive at rest. Improved prosthestic design, valve repair whenever possible, and anular enlargement procedures would be required to eliminate this size disparity.
S Westaby; R B Karp; E H Blackstone; S P Bishop
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The American journal of cardiology     Volume:  53     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1984 Feb 
Date Detail:
Created Date:  1984-03-07     Completed Date:  1984-03-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  552-6     Citation Subset:  AIM; IM    
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MeSH Terms
Body Height
Body Surface Area
Cardiomegaly / pathology
Heart Failure / pathology
Heart Valve Prosthesis*
Heart Valves / anatomy & histology*
Middle Aged
Organ Size
Prosthesis Design
Sex Factors
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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