| Adult hippocampal neurogenesis: a possible way how physical exercise counteracts stress. | |
| | |
MedLine Citation:
|
PMID: 20887683 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
It was considered that neurogenesis only occurred during the embryonic and developmental stage. This view has greatly changed since the discovery of adult neurogenesis in two brain regions: the hippocampus and the olfactory bulb. Recently, it is suggested that altered hippocampal neurogenesis is related to pathophysiology of mood disorders and mechanism of antidepressant treatments. Accumulating knowledge about the effects of physical exercise on brain function suggests a special role of adult hippocampal neurogenesis in cognitive and mental health, even though the functional significance of adult neurogenesis is still debated. The beneficial effects of running correlating with increased adult neurogenesis may provide a hint that newborn neurons may be involved, at least in part, in the counteractive mechanism of physical exercise on stress-related disorders, like depression. The present review provides an overview of recent findings to emphasize the possible involvement of hippocampal neurogenesis in mediating the beneficial effects of physical exercise on counteracting stress. |
| | |
Authors:
|
Suk-Yu Yau; Benson Wui-Man Lau; Kwok-Fai So |
Related Documents
:
|
21104863 - Voluntary exercise induces structural remodeling in the hearts of dystrophin-deficient ... 16831213 - Periodontopathic bacterial endotoxin-induced tumor necrosis factor alpha production was... 14563663 - Interaction between prostanoids and nitric oxide in regulation of systemic, pulmonary, ... |
Publication Detail:
|
Type: Journal Article Date: 2010-09-30 |
Journal Detail:
|
Title: Cell transplantation Volume: 20 ISSN: 1555-3892 ISO Abbreviation: Cell Transplant Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-03-14 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9208854 Medline TA: Cell Transplant Country: United States |
Other Details:
|
Languages: eng Pagination: 99-111 Citation Subset: IM |
Affiliation:
|
Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung, Taiwan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: An overview of concepts for cancer stem cells.
Next Document: The treatment of neurodegenerative disorders using umbilical cord blood and menstrual blood-derived ...