Document Detail


Adult and fetal wound healing.
MedLine Citation:
PMID:  17981527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mammalian wound healing is an intricate process involving the coordinated interaction of a variety of tissue types and cellular lineages. This is governed by a complex array of physical, biological and chemical signals. In adult tissue, the successful completion of wound healing inevitably results in the formation of scar. However, animal studies of embryonic tissue have shown that early gestation fetal wounds heal with complete restoration of tissue structure and function. The exact mechanisms underlying scarless healing in the fetus remain to be elucidated.
Authors:
Basil M Hantash; Longmei Zhao; Joseph A Knowles; H Peter Lorenz
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-01-01
Journal Detail:
Title:  Frontiers in bioscience : a journal and virtual library     Volume:  13     ISSN:  1093-4715     ISO Abbreviation:  Front. Biosci.     Publication Date:  2008  
Date Detail:
Created Date:  2007-11-05     Completed Date:  2007-12-11     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9709506     Medline TA:  Front Biosci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  51-61     Citation Subset:  IM    
Affiliation:
The Department of Surgery, Division of Plastic Surgery, Stanford University School of Medicine, 257 Campus Drive, Stanford, CA 94305, USA.
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MeSH Terms
Descriptor/Qualifier:
Animals
Cell Proliferation
Cicatrix
Cytokines / metabolism
Gene Expression Regulation, Developmental
Humans
Inflammation
Models, Biological
Oligonucleotide Array Sequence Analysis
Signal Transduction
Skin / embryology*,  metabolism*
Wound Healing*
Chemical
Reg. No./Substance:
0/Cytokines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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