Document Detail


Adult orbital myeloid sarcoma (granulocytic sarcoma): two cases and review of the literature.
MedLine Citation:
PMID:  23088361     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/AIMS: [corrected] To report two rare cases of orbital myeloid sarcoma in adults and discuss special features relevant to this entity.
METHODS: Complete ophthalmologic and systemic examinations followed by incisional biopsy and pathological examination.
RESULTS: Two cases of myeloid sarcoma with orbital involvement were identified. Both cases presented with a clinical picture and imaging which demonstrated infiltrative orbital masses. When combined with 8 previous reported cases, 8/10 demonstrated systemic AML involvement.
CONCLUSIONS: Orbital myeloid sarcoma is a rare entity in adults and highly associated with myelodysplastic syndromes, especially acute myelogenous leukemia (AML). It may present at any stage of AML and requires appropriate workup and treatment, though generally carries a poor prognosis.
Authors:
Deepak Mangla; Mohit Dewan; Dale R Meyer
Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2012-10-22
Journal Detail:
Title:  Orbit (Amsterdam, Netherlands)     Volume:  31     ISSN:  1744-5108     ISO Abbreviation:  Orbit     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-12     Completed Date:  2013-08-27     Revised Date:  2014-10-06    
Medline Journal Info:
Nlm Unique ID:  8301221     Medline TA:  Orbit     Country:  England    
Other Details:
Languages:  eng     Pagination:  438-40     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged, 80 and over
Biopsy
Diagnosis, Differential
Fatal Outcome
Humans
Immunohistochemistry
Magnetic Resonance Imaging
Male
Middle Aged
Orbital Neoplasms / diagnosis*,  pathology
Sarcoma, Myeloid / diagnosis*,  pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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