| Adult Evans syndrome: complete hematologic recovery with steroids and rituximab: a case report. | |
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MedLine Citation:
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PMID: 20939201 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Evans syndrome is an autoimmune disorder characterized by the simultaneous or sequential development of autoimmune hemolytic anemia and immune thrombocytopenia. It may be primary (idiopathic, or associated with other diseases. First line therapy is immunosupression. A second line therapy includes danazol and splenectomy. Rituximab was approved by the Federal Drug Administration since 1998 for the treatment of lymphomas. We report a 46-year-old-male Hispanic with Evans syndrome. He presented with severe life threatening autoimmune hemolytic anemia and subsequently developed autoimmune thrombocytopenia. After treatment with steroids and rituximab he remains in remission. This case report supports the use of rituximab in an adult patient with Evans syndrome. |
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Authors:
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Karen J Santiago-Ríos; Omayra Reyes; Alexis Cruz; Nydia Rodríguez-Pabón; William Cáceres |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Boletín de la Asociación Médica de Puerto Rico Volume: 102 ISSN: 0004-4849 ISO Abbreviation: Bol Asoc Med P R Publication Date: 2010 Apr-Jun |
Date Detail:
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Created Date: 2010-10-13 Completed Date: 2010-11-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7505267 Medline TA: Bol Asoc Med P R Country: Puerto Rico |
Other Details:
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Languages: eng Pagination: 33-6 Citation Subset: IM |
Affiliation:
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From the Hematology-Oncology Section, Department of Medicine, VA Caribbean Healthcare System, 10 Calle Casia, San Juan, Puerto Rico 00921. karensantiagorios@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hemolytic, Autoimmune
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blood,
drug therapy Antibodies, Monoclonal, Murine-Derived / therapeutic use* Humans Immunologic Factors / therapeutic use* Male Middle Aged Remission Induction Steroids / therapeutic use* Thrombocytopenia / blood, drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Monoclonal, Murine-Derived; 0/Immunologic Factors; 0/Steroids; 0/rituximab |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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