Document Detail

Adsorption of mutagens by humic acid.
MedLine Citation:
PMID:  2953067     Owner:  NLM     Status:  MEDLINE    
Humic acid inhibited the mutagenicity of various mutagens. The inhibitory effect was desmutagenic, heat-resistant and increased with an increase of the humic acid molecular weight. Typical monomeric components of humic acids had no desmutagenic effect. The desmutagenic effect of humic acid was caused by adsorption of mutagen, not by decomposition of mutagen. The adsorption activity was largest at its critical micelle concentration and the adsorbed mutagen was released by ultrasonication. Humic acids exist in natural environment in large amounts and may play an important role for natural purification by adsorption of mutagens.
T Sato; Y Ose; H Nagase; K Hayase
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Science of the total environment     Volume:  62     ISSN:  0048-9697     ISO Abbreviation:  Sci. Total Environ.     Publication Date:  1987 Apr 
Date Detail:
Created Date:  1987-06-09     Completed Date:  1987-06-09     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0330500     Medline TA:  Sci Total Environ     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  305-10     Citation Subset:  IM    
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MeSH Terms
Hot Temperature
Humic Substances / pharmacology*
Molecular Weight
Mutagenicity Tests
Reg. No./Substance:
0/Humic Substances; 0/Mutagens; 50-32-8/Benzo(a)pyrene

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