| Adrenoleukodystrophy: evidence for cytoplasmic inclusions in white blood cells. | |
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MedLine Citation:
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PMID: 3029738 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Adrenoleukodystrophy (ALD) is a progressive neurological demyelinating disease associated with adrenal insufficiency. Pathognomonic lamellar profiles and clear clefts have been observed in several organs and tissues. We describe similar ultrastructural lamellar lipid profiles in white blood cells from 2 patients with ALD. It is suggested that electron microscopy of white blood cells may be a simple and effective screening method in patients presenting with a clinical picture suggestive of ALD. |
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Authors:
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J Chemke; N Livni; E Rosenmann |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Pediatric pathology / affiliated with the International Paediatric Pathology Association Volume: 6 ISSN: 0277-0938 ISO Abbreviation: Pediatr Pathol Publication Date: 1986 |
Date Detail:
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Created Date: 1987-04-06 Completed Date: 1987-04-06 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8303527 Medline TA: Pediatr Pathol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 173-9 Citation Subset: IM |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenoleukodystrophy
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pathology* Adult Child Cytoplasm / ultrastructure* Diffuse Cerebral Sclerosis of Schilder / pathology* Humans Inclusion Bodies / ultrastructure* Lipid Metabolism Male Microscopy, Electron Neutrophils / ultrastructure* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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