| Adrenocortical insufficiency in horses and foals. | |
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MedLine Citation:
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PMID: 21392651 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The adrenal cortices produce various steroid hormones that play vital roles in several physiologic processes. Although permanent adrenocortical insufficiency is rare in all species, emerging evidence in both human and equine medicine suggests that transient reversible adrenocortical dysfunction resulting in cortisol insufficiency frequently develops during critical illness. This syndrome is termed relative adrenal insufficiency (RAI) or critical illness-related corticosteroid insufficiency (CIRCI) and can contribute substantially to morbidity and mortality associated with the primary disease. This review discusses the mechanisms, diagnosis, and clinical consequences of adrenocortical insufficiency, with particular focus on the current understanding of RAI/CIRCI in horses and foals. |
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Authors:
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Kelsey A Hart; Michelle H Barton |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Veterinary clinics of North America. Equine practice Volume: 27 ISSN: 1558-4224 ISO Abbreviation: Vet. Clin. North Am. Equine Pract. Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-03-11 Completed Date: 2011-04-26 Revised Date: 2012-04-04 |
Medline Journal Info:
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Nlm Unique ID: 8511904 Medline TA: Vet Clin North Am Equine Pract Country: United States |
Other Details:
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Languages: eng Pagination: 19-34 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Large Animal Medicine, University of Georgia College of Veterinary Medicine, 501 DW Brooks Drive, Athens, GA 30602, USA. khart4@uga.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Addison Disease
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blood,
diagnosis,
physiopathology,
veterinary* Adrenal Cortex / metabolism, physiopathology* Animals Animals, Newborn Female Horse Diseases / blood, diagnosis*, physiopathology Horses Hydrocortisone / blood, deficiency* Male |
| Grant Support | |
ID/Acronym/Agency:
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F32 GM086003-02/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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