Document Detail


Adreno-leukodystrophy with microphthalmia. A condition marked by general organ hypoplasia.
MedLine Citation:
PMID:  1222325     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 5-6/12 year old male child who was noted to have neurological impairment at birth, eventually died with widespread neurological disease. Pathological findings were compatible with adreno-leukodystrophy, but also showed microphthalmia and diffuse organ hypoplasia. A review of the clinical and pathological characteristics of adreno-leukodystrophy of previous cases and the current case suggests that the range of the disease spectrum may well involve most organs of the body. The possibility of an inherited membrane deficit is entertained.
Authors:
B I Machanic; W J Brown
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Bulletin of the Los Angeles neurological societies     Volume:  40     ISSN:  0024-659X     ISO Abbreviation:  Bull Los Angeles Neurol Soc     Publication Date:  1975 Jul 
Date Detail:
Created Date:  1976-07-06     Completed Date:  1976-07-06     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0064572     Medline TA:  Bull Los Angeles Neurol Soc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  116-23     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / pathology*
Adrenal Glands / abnormalities*
Brain / pathology*
Child, Preschool
Diffuse Cerebral Sclerosis of Schilder / pathology*
Humans
Male
Microphthalmos / pathology*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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