| Adrenaline synthesizing neurons in the rostral ventrolateral medulla: a possible role in tonic vasomotor control. | |
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MedLine Citation:
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PMID: 6616243 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Adrenaline-containing neurons of the rostral ventrolateral medulla (the C1 group) project selectively to autonomic spinal neurons in rats. Stimulation of these neurons electrically or chemically elevates arterial pressure, while neuronal blockade by microinjection of tetrodotoxin bilaterally drops arterial pressure to levels comparable to those produced by spinal cord transection. Adrenaline neurons of the ventral medulla appear necessary for maintaining normal levels of blood pressure, and thus may constitute a tonic vasomotor center. |
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Authors:
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C A Ross; D A Ruggiero; T H Joh; D H Park; D J Reis |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Brain research Volume: 273 ISSN: 0006-8993 ISO Abbreviation: Brain Res. Publication Date: 1983 Aug |
Date Detail:
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Created Date: 1983-11-23 Completed Date: 1983-11-23 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0045503 Medline TA: Brain Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 356-61 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Pressure Brain Mapping Epinephrine / physiology* Heart Rate Medulla Oblongata / enzymology, physiology* Neural Pathways / physiology Phenylethanolamine N-Methyltransferase / metabolism Rats Spinal Cord / physiology* Vasomotor System / physiology* |
| Grant Support | |
ID/Acronym/Agency:
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HL 07378/HL/NHLBI NIH HHS; HL 07379/HL/NHLBI NIH HHS; HL 18974/HL/NHLBI NIH HHS |
| Chemical | |
Reg. No./Substance:
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51-43-4/Epinephrine; EC 2.1.1.28/Phenylethanolamine N-Methyltransferase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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