Document Detail

Adrenal pheochromocytoma-ganglioneuroma producing catecholamines and various neuropeptides.
MedLine Citation:
PMID:  3188992     Owner:  NLM     Status:  MEDLINE    
A 65-year-old woman presenting with back pain, difficulties in walking and watery diarrhea. A right adrenal tumor and high excretion of catecholamines were found. Laboratory examinations showed raised levels of vasoactive intestinal polypeptide, pancreatic polypeptide, gastrin and calcitonin. Histology showed a combined pheochromocytoma-ganglioneuroma. The neoplastic cell population was immunohistochemically shown to contain tyrosine hydroxylase, neuropeptide Y, met-enkephalin, substance P, vasoactive intestinal polypeptide, calcitonin and calcitonin gene-related peptide. Postoperatively, the patient recovered fully and the hormone levels returned to normal.
J Salmi; M Pelto-Huikko; O Auvinen; A L Karvonen; J Saaristo; I Paronen; L Pöyhönen; S Seppänen
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta medica Scandinavica     Volume:  224     ISSN:  0001-6101     ISO Abbreviation:  Acta Med Scand     Publication Date:  1988  
Date Detail:
Created Date:  1988-12-16     Completed Date:  1988-12-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370330     Medline TA:  Acta Med Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  403-8     Citation Subset:  IM    
Department of Internal Medicine, University Central Hospital of Tampere, Finland.
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MeSH Terms
Adrenal Gland Neoplasms / pathology,  secretion*,  surgery
Catecholamines / secretion*
Ganglioneuroma / pathology,  secretion*,  surgery
Neuropeptides / secretion*
Pheochromocytoma / pathology,  secretion*,  surgery
Reg. No./Substance:
0/Catecholamines; 0/Neuropeptides

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