| Adrenal medulla transplantation into the putamen in Parkinson's disease. | |
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MedLine Citation:
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PMID: 2320218 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Autologous adrenal medulla was transplanted into the putamen of a patient with severe Parkinson's disease. After the operation, the patient's akinesia and rigidity decreased and the duration of action of L-dopa treatment was prolonged. The effect lasted for only 6 months, however, following which the patient's condition gradually began to deteriorate again, returning to the preoperative state by 12 months after surgery. This paper discusses possible reasons why the effect was only temporary. |
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Authors:
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J Takeuchi; Y Takebe; T Sakakura; Y Hara; T Yasuda; T Imai |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Neurosurgery Volume: 26 ISSN: 0148-396X ISO Abbreviation: Neurosurgery Publication Date: 1990 Mar |
Date Detail:
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Created Date: 1990-05-08 Completed Date: 1990-05-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7802914 Medline TA: Neurosurgery Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 499-503 Citation Subset: IM |
Affiliation:
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Department of Neurosurgery, Utano National Hospital, Kyoto, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Medulla
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transplantation* Female Humans Levodopa / therapeutic use Middle Aged Parkinson Disease / drug therapy, metabolism, surgery* Putamen Transplantation, Heterotopic |
| Chemical | |
Reg. No./Substance:
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0/Levodopa |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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