| Adrenal hypofunction and trisomy 18. | |
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MedLine Citation:
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PMID: 6700888 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Three cases of trisomy 18 are described, each with evidence of diminished fetoplacental function, specifically reduced 24-hour maternal urinary estrogen. All three infants died within three months and showed gross and microscopic evidence of hypoplasia of the fetal adrenal cortical zone. This abnormality is consistent with and helps explain the increased incidence of obstetric intervention and prolonged pregnancy in this syndrome. |
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Authors:
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M Turner; C O'Herlihy |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 63 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1984 Mar |
Date Detail:
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Created Date: 1984-03-27 Completed Date: 1984-03-27 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 84S-85S Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abnormalities, Multiple
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diagnosis* Adrenal Glands / abnormalities* Adrenal Insufficiency / diagnosis*, etiology Adult Chromosomes, Human, 16-18* Estrogens / urine Female Fetal Diseases / etiology Humans Infant, Newborn Pregnancy Trisomy* |
| Chemical | |
Reg. No./Substance:
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0/Estrogens |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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