| Adrenal gland volume measurement in septic shock and control patients: a pilot study. | |
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MedLine Citation:
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PMID: 20521055 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: To compare adrenal gland volume in septic shock patients and control patients by using semi-automated volumetry. METHODS: Adrenal gland volume and its inter-observer variability were measured with tomodensitometry using semi-automated software in 104 septic shock patients and in 40 control patients. The volumes of control and septic shock patients were compared and the relationship between volume and outcome in intensive care was studied. RESULTS: The mean total volume of both adrenal glands was 7.2 ± 2.0 cm(3) in control subjects and 13.3 ± 4.7 cm(3) for total adrenal gland volume in septic shock patients (p < 0.0001). Measurement reproducibility was excellent with a concordance correlation coefficient value of 0.87. The increasing adrenal gland volume was associated with a higher rate of survival in intensive care. CONCLUSION: The present study reports that with semi-automated software, adrenal gland volume can be measured easily and reproducibly. Adrenal gland volume was found to be nearly double in sepsis compared with control patients. The absence of increased volume during sepsis would appear to be associated with a higher rate of mortality and may represent a prognosis factor which may help the clinician to guide their strategy. |
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Authors:
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Stephanie Nougaret; B Jung; S Aufort; G Chanques; S Jaber; B Gallix |
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Publication Detail:
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Type: Journal Article Date: 2010-06-04 |
Journal Detail:
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Title: European radiology Volume: 20 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-16 Completed Date: 2011-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 2348-57 Citation Subset: IM |
Affiliation:
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Department of Abdominal Imaging, CHU Montpellier, Hôpital Saint Eloi, 80 avenue Augustin Fliche, 34295, Montpellier, Cedex 5, France. stephanienougaret@free.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Glands
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pathology* Aged Automation Case-Control Studies Densitometry / methods Female Humans Male Middle Aged Pilot Projects Prognosis Reproducibility of Results Shock, Septic / pathology* Tomography, X-Ray Computed / methods |
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