| Adolescent build and diabetes: the Guangzhou Biobank Cohort Study. | |
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MedLine Citation:
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PMID: 21130371 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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PURPOSE: With economic development, there is an emerging epidemic of diabetes in China despite relatively low levels of obesity. Muscle mass, for which adolescence is a key developmental window, may reduce vulnerability to diabetes. We examined the association of recalled adolescent build with diabetes in a large sample from the developing country setting of southern China. METHODS: We used multivariable regression in cross-sectional data (2005-2008), from the Guangzhou Biobank Cohort Study (phases 2 and 3) for 19,524 older (≥ 50 years) Chinese to examine the adjusted associations of recalled adolescent relative weight (light [n = 6843], average [n = 9529], and heavy [n = 3152]) with clinically measured diabetes. RESULTS: As older adults, heavy adolescents had a lower risk of diabetes (odds ratio = 0.86, 95% confidence interval: 0.75-0.99) than light adolescents adjusted for age, sex, education, smoking, leg length, and seated height. This association was stronger after additional adjustment for waist/hip ratio and body mass index. CONCLUSIONS: Poor living conditions during adolescence, resulting in low muscle mass, could contribute to vulnerability to diabetes, which, if confirmed, could be relevant to the emerging epidemic of diabetes in the developing world, as well as to minorities and migrants elsewhere. |
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Authors:
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C Mary Schooling; Chaoqiang Jiang; Weisen Zhang; Tai Hing Lam; Kar Keung Cheng; Gabriel M Leung |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Annals of epidemiology Volume: 21 ISSN: 1873-2585 ISO Abbreviation: Ann Epidemiol Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2010-12-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9100013 Medline TA: Ann Epidemiol Country: United States |
Other Details:
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Languages: eng Pagination: 61-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier Inc. All rights reserved. |
Affiliation:
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School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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