| Admission base excess as a predictor of transfusion requirement and mortality in dogs with blunt trauma: 52 cases (2007-2009). | |
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MedLine Citation:
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PMID: 23110572 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the ability of admission base excess (ABE) to predict blood transfusion requirement and mortality in dogs following blunt trauma. DESIGN: Retrospective study 2007-2009. SETTING: University Veterinary Teaching Hospital. ANIMALS: Fifty-two dogs admitted to the intensive care unit for treatment following blunt trauma. MEASUREMENTS AND MAIN RESULTS: Animals requiring red blood cell transfusion (N = 8) had significantly lower ABE than those not requiring transfusion (N = 44; median base excess [BE] = -8.4 versus -4.7, P = .0034), while there was no difference in admission packed cell volume (PCV) or age. Animals that died or were euthanized due to progression of signs (N = 5) had lower median ABE than those that survived (N = 47; median BE = -7.3 versus -4.9, P = 0.018). Admission PCV and age were not significantly different between survivors and nonsurvivors. Receiver operator characteristic curve analysis showed an ABE cutoff of -6.6 was 88% sensitive and 73% specific for transfusion requirement (P < 0.001), and a cutoff of -7.3 was 81% sensitive and 80% specific for survival (P < 0.001). Multivariate logistic regression analysis demonstrated that ABE was a predictor of transfusion requirement that was independent of overall severity of injury as measured by the Animal Triage Trauma (ATT) score, but a similar analysis showed that only ATT was an independent predictor of survival. CONCLUSIONS: The ABE in dogs with blunt trauma was a predictor of mortality and blood transfusion requirement within 24 hours. |
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Authors:
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Jenefer R Stillion; Daniel J Fletcher |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) Volume: 22 ISSN: 1476-4431 ISO Abbreviation: J Vet Emerg Crit Care (San Antonio) Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101152804 Medline TA: J Vet Emerg Crit Care (San Antonio) Country: United States |
Other Details:
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Languages: eng Pagination: 588-94 Citation Subset: IM |
Copyright Information:
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© Veterinary Emergency and Critical Care Society 2012. |
Affiliation:
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From the Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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