Document Detail


Admission base excess as a predictor of transfusion requirement and mortality in dogs with blunt trauma: 52 cases (2007-2009).
MedLine Citation:
PMID:  23110572     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To evaluate the ability of admission base excess (ABE) to predict blood transfusion requirement and mortality in dogs following blunt trauma.
DESIGN: Retrospective study 2007-2009.
SETTING: University Veterinary Teaching Hospital.
ANIMALS: Fifty-two dogs admitted to the intensive care unit for treatment following blunt trauma.
MEASUREMENTS AND MAIN RESULTS: Animals requiring red blood cell transfusion (N = 8) had significantly lower ABE than those not requiring transfusion (N = 44; median base excess [BE] = -8.4 versus -4.7, P = .0034), while there was no difference in admission packed cell volume (PCV) or age. Animals that died or were euthanized due to progression of signs (N = 5) had lower median ABE than those that survived (N = 47; median BE = -7.3 versus -4.9, P = 0.018). Admission PCV and age were not significantly different between survivors and nonsurvivors. Receiver operator characteristic curve analysis showed an ABE cutoff of -6.6 was 88% sensitive and 73% specific for transfusion requirement (P < 0.001), and a cutoff of -7.3 was 81% sensitive and 80% specific for survival (P < 0.001). Multivariate logistic regression analysis demonstrated that ABE was a predictor of transfusion requirement that was independent of overall severity of injury as measured by the Animal Triage Trauma (ATT) score, but a similar analysis showed that only ATT was an independent predictor of survival.
CONCLUSIONS: The ABE in dogs with blunt trauma was a predictor of mortality and blood transfusion requirement within 24 hours.
Authors:
Jenefer R Stillion; Daniel J Fletcher
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)     Volume:  22     ISSN:  1476-4431     ISO Abbreviation:  J Vet Emerg Crit Care (San Antonio)     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-31     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101152804     Medline TA:  J Vet Emerg Crit Care (San Antonio)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  588-94     Citation Subset:  IM    
Copyright Information:
© Veterinary Emergency and Critical Care Society 2012.
Affiliation:
From the Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY.
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