Document Detail


Administration of recombinant human erythropoietin in patients with gynecological cancer before radical surgery.
MedLine Citation:
PMID:  16108399     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this prospective study was to investigate the efficacy of preoperative administration of recombinant human erythropoietin in patients with gynecological cancer. METHODS: The study included 38 women with gynecological cancer who were divided randomly in two groups. Study group A included 20 women with gynecological cancer who received recombinant human erythropoietin (rHuEPO) plus iron supplementation for ten days before surgery and five days postoperatively. Group B (controls) included 18 patients who received only iron supplementation for the same time period. Blood samples were obtained on days -10, -3, 0, +3, +5, +10. RESULTS: The mean hemoglobin level was significantly higher in group A than in group B on the day of the operation and remained significantly higher postoperatively while an inverse relationship was observed for mean ferritin values in the two groups. CONCLUSION: Preoperative administration of rHuEPO in patients with gynecological cancer seems to be effective in the blood management of these patients.
Authors:
V Dousias; T Stefos; I Navrozoglou; I Staikos; A Ditto; E Paraskevaidis
Related Documents :
22563189 - Antifibrotic effect of aloe vera in viral infection-induced hepatic periportal fibrosis.
2009719 - The outcome of renal transplantation in children without prolonged pre-transplant dialy...
19552799 - Factors associated with septic shock and mortality in generalized peritonitis: comparis...
21894389 - Hourly activity of lutzomyia neivai in the endemic zone of cutaneous leishmaniasis in t...
10586429 - Low dose desferrioxamine can improve erythropoiesis in iron-overload hemodialysis patie...
8255009 - Effects of high-dose vitamin b6 therapy on microcytic and hypochromic anemia in hemodia...
11407799 - Prevention of venous thromboembolic disease following primary total knee arthroplasty. ...
18827239 - The nexgen lps-flex to the knee prosthesis at a minimum of three years.
21343689 - Foot mobility and plantar fascia elasticity in patients with plantar fasciitis.
Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Clinical and experimental obstetrics & gynecology     Volume:  32     ISSN:  0390-6663     ISO Abbreviation:  Clin Exp Obstet Gynecol     Publication Date:  2005  
Date Detail:
Created Date:  2005-08-19     Completed Date:  2005-11-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7802110     Medline TA:  Clin Exp Obstet Gynecol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  129-31     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, University Hospital of Ioannina, Ioannina, Greece.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Confidence Intervals
Dose-Response Relationship, Drug
Drug Administration Schedule
Erythropoietin, Recombinant / administration & dosage*
Female
Follow-Up Studies
Genital Neoplasms, Female / drug therapy*,  mortality,  pathology,  surgery*
Gynecologic Surgical Procedures / methods*,  mortality
Humans
Iron Compounds / administration & dosage*
Middle Aged
Neoplasm Staging
Preoperative Care
Probability
Prospective Studies
Reference Values
Risk Assessment
Survival Analysis
Treatment Outcome
Chemical
Reg. No./Substance:
0/Erythropoietin, Recombinant; 0/Iron Compounds

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Epidural anesthesia from an obstetrics point of view.
Next Document:  Uterine arteriovenous malformation: a case report diagnosed by sonohysterography.