| Administration of copper oxide wire particles in a capsule or feed for gastrointestinal nematode control in goats. | |
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MedLine Citation:
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PMID: 19945224 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Widespread anthelmintic resistance in small ruminants has necessitated alternative means of gastrointestinal nematode (GIN) control. The objective was to determine the effectiveness of copper oxide wire particles (COWP) administered as a gelatin capsule or in a feed supplement to control GIN in goats. In four separate experiments, peri-parturient does (n=36), yearling does (n=25), weaned kids (n=72), and yearling bucks (n=16) were randomly assigned to remain untreated or administered 2g COWP in a capsule (in Experiments 1, 2, and 3) or feed supplement (all experiments). Feces and blood were collected every 7 days between Days 0 and 21 (older goats) or Day 42 (kids) for fecal egg counts (FEC) and blood packed cell volume (PCV) analyses. A peri-parturient rise in FEC was evident in the untreated does, but not the COWP-treated does (COWP x date, P<0.02). In yearling does, FEC of the COWP-treated does tended to be lower than the untreated (COWP, P<0.02). FEC of COWP-treated kids were reduced compared with untreated kids (COWP x date, P<0.001). FEC of treated and untreated bucks were similar, but Haemonchus contortus was not the predominant nematode in these goats. However, total worms were reduced in COWP-fed bucks (P<0.03). In summary, it appeared that COWP in the feed was as effective as COWP in a gelatin capsule to reduce FEC in goats. COWP administration may have a limited effect where H. contortus is not the predominant nematode. |
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Authors:
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J M Burke; F Soli; J E Miller; T H Terrill; S Wildeus; S A Shaik; W R Getz; M Vanguru |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. Date: 2009-11-10 |
Journal Detail:
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Title: Veterinary parasitology Volume: 168 ISSN: 1873-2550 ISO Abbreviation: Vet. Parasitol. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-08 Completed Date: 2010-06-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7602745 Medline TA: Vet Parasitol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 346-50 Citation Subset: IM |
Affiliation:
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Dale Bumpers Small Farms Research Center, USDA, ARS, Booneville, AR 72927, USA. joan.burke@ars.usda.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Oral Animals Capsules Copper / administration & dosage* Female Gastrointestinal Diseases / drug therapy, prevention & control, veterinary* Goat Diseases / drug therapy*, parasitology*, prevention & control Goats Male Nematoda Nematode Infections / drug therapy, prevention & control, veterinary* Pregnancy |
| Chemical | |
Reg. No./Substance:
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0/Capsules; 1317-38-0/cupric oxide; 7440-50-8/Copper |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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