| Administration of clomiphene citrate in patients with polycystic ovary syndrome, without inducing withdrawal bleeding, achieves comparable treatment characteristics and outcome. | |
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MedLine Citation:
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PMID: 19732872 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In an attempt to evaluate the effect of random timing of the start of clomiphene citrate (CC) treatment in anovulatory patients with polycystic ovary syndrome on treatment characteristics and outcome, with no regard to time of menstruation, we studied 291 women in their first CC treatment cycle. Duration of treatment was shorter by 2 days and number of leading follicles was higher when treatment was started late (7-29 days from starting a bleed, as compared with day 5), but no effect of starting day was observed on response rate to CC, maximal E(2) level, endometrial thickness, and pregnancy rate. |
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Authors:
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Jacob Farhi; Raoul Orvieto; Roy Homburg |
Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study Date: 2009-09-03 |
Journal Detail:
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Title: Fertility and sterility Volume: 93 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2010 Apr |
Date Detail:
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Created Date: 2010-03-30 Completed Date: 2010-04-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 2077-9 Citation Subset: IM |
Copyright Information:
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Copyright 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Infertility and IVF Unit, Department of Obstetrics and Gynecology, Helen Schneider Hospital for Women, Rabin Medical Center, Petach Tikva, Israel. j_farhi@yahoo.com |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Clomiphene / administration & dosage* Drug Administration Schedule Endometrium / drug effects, pathology Estradiol / blood Female Fertility Agents, Female / administration & dosage Humans Infertility, Female / blood, drug therapy*, etiology, pathology Male Menstruation / drug effects*, physiology Ovarian Follicle / drug effects, physiology Ovulation Induction / methods* Polycystic Ovary Syndrome / blood, complications, drug therapy*, pathology Pregnancy Pregnancy Rate Treatment Outcome Withholding Treatment Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Fertility Agents, Female; 50-28-2/Estradiol; 911-45-5/Clomiphene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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