Document Detail

Adjuvant radiotherapy in the treatment of breast cancer.
MedLine Citation:
PMID:  9703786     Owner:  NLM     Status:  MEDLINE    
Recent studies on the impact of adjuvant radiotherapy on local control, survival and quality of life in patients with breast cancer have been evaluated. Following these studies, breast conserving surgery with subsequent radiation therapy is the standard treatment for early breast cancer. In advanced disease, radiation is indicated for patients with T3- or T4 and/or with four or more positive lymph nodes. In general, radiotherapy leads to a 2-4 fold reduction of local relapse. In addition, there is considerable evidence that radiotherapy is associated with a higher overall survival. In elderly women postoperative radiotherapy should not be withheld. An extensive intraductal component (EIC) or multicentric disease can be compatible with breast conserving therapy if surgery has been completed. Self assessment of patients rated the cosmetic results of breast conserving therapy higher than mastectomy and breast reconstruction.
C F Hess; H Schmidberger
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Anticancer research     Volume:  18     ISSN:  0250-7005     ISO Abbreviation:  Anticancer Res.     Publication Date:    1998 May-Jun
Date Detail:
Created Date:  1998-08-28     Completed Date:  1998-08-28     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8102988     Medline TA:  Anticancer Res     Country:  GREECE    
Other Details:
Languages:  eng     Pagination:  2213-4     Citation Subset:  IM    
Klinik fur Strahlentherapie und Radioonkologie, Göttingen, Germany.
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MeSH Terms
Breast Neoplasms / drug therapy,  radiotherapy*,  surgery
Combined Modality Therapy
Follow-Up Studies
Radiotherapy, Adjuvant

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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