Document Detail


Adjuvant immunotherapy for melanoma and colorectal cancers.
MedLine Citation:
PMID:  11254868     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Immune approaches to the therapy of colorectal cancer and melanoma have substantially evolved over the past years, from treating patients with nonspecific immune stimulants to a focus on the use of tumor-associated antigens (TAAs) either by passive immune therapy with antibodies targeted directly to tumor cells or by active immune therapy via vaccination with tumor cells, tumor cell lysates, peptides, carbohydrates, gene constructs encoding proteins, or anti-idiotype antibodies that mimic TAAs. We review the different immunotherapeutic approaches to the treatment of melanoma and colorectal cancers, and summarize relevant clinical trials.
Authors:
M M Safa; K A Foon
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in oncology     Volume:  28     ISSN:  0093-7754     ISO Abbreviation:  Semin. Oncol.     Publication Date:  2001 Feb 
Date Detail:
Created Date:  2001-03-01     Completed Date:  2001-03-29     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0420432     Medline TA:  Semin Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  68-92     Citation Subset:  IM    
Affiliation:
Barrett Cancer Center and the Department of Internal Medicine, Cincinnati, OH 45267, USA.
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Monoclonal / therapeutic use
Cancer Vaccines
Colorectal Neoplasms / immunology,  therapy*
Humans
Immunotherapy / methods*
Melanoma / immunology,  therapy*
Radioimmunotherapy / methods
Chemical
Reg. No./Substance:
0/Antibodies, Monoclonal; 0/Cancer Vaccines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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