Document Detail


Adjuvant chemotherapy in node negative breast cancer: patterns of use and oncologists' preferences.
MedLine Citation:
PMID:  10907961     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A worldwide variation in policy is seen regarding adjuvant systemic treatment for node negative breast cancer (NNBC). After the first presentations of the 10-year EBCTCG results, a study was carried out in the Netherlands to assess patterns of care and to obtain the views of oncologists as to what constitutes a worthwhile benefit from treatment. METHODS: A questionnaire regarding patterns of use of and preferences for adjuvant chemotherapy in younger women was mailed to surgical, medical and radiation oncologists in the Netherlands. RESULTS: Thirty-five percent stated that NNBC patients under 50 in their hospital never received adjuvant chemotherapy. The majority considered a 10-year survival gain of 6%-10% sufficient to warrant the use of chemotherapy in patients under 50. Surgical oncologists required a larger benefit from treatment than radiotherapists and medical oncologists. The more frequently oncologists treated patients in a research context, the less benefit they required from treatment to make it worthwhile. CONCLUSIONS: Data such as these are valuable input into the process of guideline development, and may help discussion within the profession as to what benefit offsets the burden of treatment.
Authors:
A M Stiggelbout; J C de Haes; C J van de Velde
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Annals of oncology : official journal of the European Society for Medical Oncology / ESMO     Volume:  11     ISSN:  0923-7534     ISO Abbreviation:  Ann. Oncol.     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-12-28     Completed Date:  2000-12-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9007735     Medline TA:  Ann Oncol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  631-3     Citation Subset:  IM    
Affiliation:
Department of Medical Decision Making, Leiden University Medical Center, The Netherlands. stiggelbout@rullf2.medfac.leidenuniv.nl
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MeSH Terms
Descriptor/Qualifier:
Adult
Attitude of Health Personnel*
Breast Neoplasms / drug therapy*
Chemotherapy, Adjuvant
Female
Health Care Surveys
Health Policy
Humans
Lymph Nodes / pathology*
Medical Oncology
Physician's Practice Patterns / statistics & numerical data*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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