Document Detail

Adjustment to Volume or Pressure Targeted Non-Invasive Ventilation in Patients With Chest Wall Deformity: A Pilot Study.
MedLine Citation:
PMID:  21513604     Owner:  NLM     Status:  Publisher    
BACKGROUND AND OBJECTIVE: While chronic non-invasive ventilation is an effective treatment in patients with chronic respiratory failure due to chest wall deformity, it is unknown whether the time to adjust to chronic ventilation depends on the type of ventilation. The aim of this study was to compare volume and pressure ventilation in these patients and to determine which type of non-invasive ventilation is the more easy to implement. METHODS: Thirteen ventilator-naïve patients were randomized to receive either volume or pressure targeted nocturnal ventilation. Primary outcome was the number of days needed to achieve successful establishment, defined as both adequate adjustment as well as effective ventilation. Effectiveness of ventilation was monitored by overnight arterial blood gas registration. RESULTS: Two patients switched from volume to pressure ventilation due to lack of tolerance. Successful establishment on non-invasive ventilation was found in both groups after a median of 6.0 days. Improvements in both PaCO₂ and PaO₂ were not significantly different between both treatments at all time points, neither were changes over time. CONCLUSIONS: This pilot study showed no difference in days needed to achieve successful establishment in either volume- or pressure ventilation in patients with chest wall deformity. Two patients switched successfully from volume to pressure non-invasive ventilation suggesting that they preferred the latter.
Fransien M Struik; Marieke L Duiverman; Petra M Meijer; Jellie A Nieuwenhuis; Huib Kerstjens; Peter J Wijkstra
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-4-19
Journal Detail:
Title:  Respiratory care     Volume:  -     ISSN:  0020-1324     ISO Abbreviation:  -     Publication Date:  2011 Apr 
Date Detail:
Created Date:  2011-4-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7510357     Medline TA:  Respir Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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