| Adjunctive therapy in Parkinson's disease: the role of rasagiline. | |
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MedLine Citation:
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PMID: 22802692 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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Parkinson's disease is the second most common neurodegenerative disorder, currently affecting 1.5 million people in the US. In this review, we describe the diagnostic and pathological features of Parkinson's disease, as well as its clinical course. We then review pharmacologic treatments for the disease, with a particular focus on therapies adjunctive to levodopa and specifically the role of rasagiline. We review the four pivotal rasagiline trials, and discuss rasagiline and its use as adjunctive therapy for Parkinson's disease. Finally, we discuss potential side effects, drug interactions, and other practical aspects concerning the use of rasagiline in Parkinson's disease. |
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Authors:
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Kathryn D Gaines; Vanessa K Hinson |
Publication Detail:
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Type: Journal Article Date: 2012-07-02 |
Journal Detail:
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Title: Neuropsychiatric disease and treatment Volume: 8 ISSN: 1178-2021 ISO Abbreviation: Neuropsychiatr Dis Treat Publication Date: 2012 |
Date Detail:
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Created Date: 2012-07-17 Completed Date: 2012-08-23 Revised Date: 2013-04-01 |
Medline Journal Info:
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Nlm Unique ID: 101240304 Medline TA: Neuropsychiatr Dis Treat Country: New Zealand |
Other Details:
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Languages: eng Pagination: 285-94 Citation Subset: - |
Affiliation:
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Department of Neurology, Aurora Advanced Healthcare, Milwaukee, WI. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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